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WebOct 3, 2024 · So when we start medicines and move someone from, let's say, a blood pressure of 160 or 170 systolic, down to 140 or 130, yes, you may feel tired when you start taking the medicine. That's natural. That's just the body adjusting to living at a lower blood pressure. But that effect goes away after 10 days to two weeks. WebJul 18, 2024 · Systolic: The first, or top, number measures the pressure in your arteries when your heart beats. Diastolic: The second, or bottom, number measures the pressure in your … WebOct 27, 2024 · Diuretics remove extra water and sodium (salt) from your body. This lowers the amount of fluid in your blood. Diuretics are often used with other high blood pressure medicines, sometimes in one combined … batavia downs kentucky derby gala